Here is a timeline of the events that led her to a New York courtroom to face sex trafficking charges.
– 1961 to 1980s
Born not far from Paris, Maxwell spent her childhood at her family’s sprawling mansion of Headington Hill Hall in Oxfordshire.
She attended the exclusive Marlborough College – one of the most expensive public schools in the UK – before studying at Balliol College, Oxford.
After graduation, Maxwell held various posts in her father’s companies and was a prominent figure on the London social scene.
November 5: Maxwell’s father Robert Maxwell dies after falling from his yacht “Lady Ghislaine” near the Canary Islands.
Maxwell reportedly meets Epstein for the first time at a party in New York.
Accuser Jane alleges she meets Maxwell for the first time while sat at a picnic table at a summer arts camp.
Jane alleges sexual contact with Epstein began later that year at the age of 14.
Accuser Kate alleges she meets Maxwell for the first time in Paris at the age of 17.
Kate claims she then went to Maxwell’s London town house and rubbed Epstein’s shoulders two weeks later.
December: Accuser Annie Farmer meets Jeffrey Epstein while visiting her sister Maria in New York.
April: Annie Farmer visits Epstein’s New Mexico house where she alleges Maxwell told her to undress and rubbed her breasts during a massage.
November 11: Epstein’s former pilot David Rodgers makes first record of Jane flying on Epstein’s private plane.
October: Epstein wires 18.3 million dollars to Maxwell.
The Duke of York and Ghislaine Maxwell were seen on holiday with Epstein at Donald Trump’s Mar-a-Lago Club in Palm Beach, Florida.
Epstein and Maxwell attended a party at Windsor Castle hosted by the Queen to mark Andrew’s 40th birthday, the Princess Royal’s 50th, the Queen Mother’s 100th and Princess Margaret’s 70th.
December 11: Mr Rodgers makes first record of Virginia Roberts flying on Epstein’s private plane.
Virginia Roberts, also known as Virginia Giuffre, was groomed by Epstein between 2000 and 2002.
She claims she was forced to have sex with Andrew three times in 2001, with the first encounter allegedly taking place in Maxwell’s London townhouse.
Ms Roberts claims to have had sex with Andrew on two more occasions, at Epstein’s New York home and at an “orgy” on his private island in the Caribbean.
She does not go public with her allegations until 2010.
The duke has categorically denied he had any form of sexual contact or relationship with Ms Giuffre.
September 17: Hard drives seized from Epstein’s New York home in 2019 shows a computer account linked to Maxwell created an advert for a massage therapist on this date.
Accuser Carolyn claims she meets Virginia Roberts and around two weeks later is taken to meet Epstein for the first time at the age of 14.
March: Carolyn pauses her visits to Epstein after becoming a mother.
Police receive their first complaint about Epstein for sexual abuse of minors and an early FBI investigation identified around 40 victims.
Despite the growing mountain of evidence against him, US prosecutors bring just one charge of soliciting prostitution from an under-age girl, for which he served just 13 months of an 18-month prison sentence.
Carolyn sues Epstein and is awarded 250,000 dollars.
Following Epstein’s release from jail, the Duke of York is photographed with him in New York’s Central Park.
Further footage emerges years later, reportedly shot on December 6 2010, showing him inside Epstein’s Manhattan mansion, from where he is seen looking out from a large door at the property.
Kate testifies this was the last time she had contact with Epstein.
July 6: Epstein is arrested in New Jersey, accused of trafficking under-age girls for sex.
August 10: Epstein is found dead in his prison cell
Maxwell maintains a low profile, and is rumoured to be staying at the home of a former partner in a small coastal town in Massachusetts.
Five days after Epstein’s death photos emerge of Maxwell apparently dining in a fast food restaurant in Los Angeles, although the pictures are later exposed as fakes.
July 3: Maxwell is arrested in New Hampshire.
April 23: Maxwell appears in court for the first time and is denied bail.
November 29: The trial at a Federal court in the Southern District of New York begins.