Gardaí at Carrick-on-Shannon in County Leitrim are investigating the fatal road traffic collision, which occurred at approximately 3pm this afternoon.
The incident occurred between Fenagh and Ballinamore on the R202 when a car and a motorcycle were in collision.
The male motorcyclist - a man in his 20s - was pronounced dead at the scene.
His body has been removed to Sligo General Hospital. No other injuries were reported.
The road remains closed to facilitate a forensic collision investigation and local diversions are in place.
Any witnesses or anyone with any information is asked to contact Carrick-on-Shannon Garda Station on 071-9650510, the Garda Confidential Line on 1800-666-111, or any Garda station.