They say the 31-year-old woman and the young boy were shot in the head Thursday, becoming Baltimore's 37th and 38th homicide victims so far this month.
With one weekend left to go, Baltimore is already suffering its deadliest month in 15 years.
Officers say they responded to a report of a shooting on Upmanor Road Thursday morning and found both victims, who were pronounced dead at the scene. Homicide detectives are investigating.
Baltimore has suffered a surge in gun violence and a sharp drop in arrests since the death of Freddie Gray from injuries he suffered in police custody unleashed protests and prompted closer scrutiny of police practices.
“I’m afraid to go outside,” West Baltimore resident Antoinette Perrine told the Associated Press.
“It’s so bad, people are afraid to let their kids outside. People wake up with shots through their windows. Police used to sit on every corner, on the top of the block. These days? They’re nowhere.”