Gardai are concerned for the welfare of Michael Anesu Nhema (33), who was last seen at approximately 9am on Tuesday at Branswood, Athy, in County Kildare.
The 33-year-old, who is originally from Zimbabwe, is described as 5' 6" in height, of slight build, with black hair and brown eyes.
Gardai have no description of clothes he may have been wearing.
He may be driving a black Audi A4 with registration plate 131-D, a Garda spokesperson said.
Michael's family and Gardai are very concerned for his welfare and are appealing for anyone with information to contact Athy Garda Station on 059 8631669, the Garda Confidential Line 1800 666 111 or any Garda station.